2ROR
Solution structure of the VAV1 SH2 domain complexed with a tyrosine-phosphorylated peptide from SLP76
Summary for 2ROR
Entry DOI | 10.2210/pdb2ror/pdb |
Descriptor | Proto-oncogene vav, 15-meric peptide from Lymphocyte cytosolic protein 2 (2 entities in total) |
Functional Keywords | sh2 domain, protein-peptide complex, phosphorylated peptide recognition, phosphotyrosine binding domain, signal transduction, guanine-nucleotide releasing factor, metal-binding, phorbol-ester binding, phosphoprotein, proto-oncogene, sh3 domain, zinc, zinc-finger, signaling protein, structural genomics, nppsfa, national project on protein structural and functional analyses, riken structural genomics/proteomics initiative, rsgi |
Biological source | Homo sapiens (human) More |
Cellular location | Cytoplasm (Probable): Q13094 |
Total number of polymer chains | 2 |
Total formula weight | 17289.93 |
Authors | Tanaka, M.,Kasai, T.,Koshiba, S.,Kigawa, T.,Yokoyama, S.,RIKEN Structural Genomics/Proteomics Initiative (RSGI) (deposition date: 2008-04-08, release date: 2009-04-21, Last modification date: 2022-03-16) |
Primary citation | Kasai, T.,Tanaka, M.,Koshiba, S.,Kigawa, T.,Yokoyama, S. Solution structure of the VAV1 SH2 domain complexed with a tyrosine-phosphorylated peptide from SLP76 To be Published, |
Experimental method | SOLUTION NMR |
Structure validation
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