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2REZ

Tetracenomycin ARO/CYC NaI Structure

Summary for 2REZ
Entry DOI10.2210/pdb2rez/pdb
Related2RER 2RES
DescriptorMultifunctional cyclase-dehydratase-3-O-methyl transferase tcmN, ACETATE ION, IODIDE ION, ... (4 entities in total)
Functional Keywordstetracenomycin, polyketide, aromatase, cyclase, dehydratase, helix-grip, double-hot-dog, antibiotic biosynthesis, methyltransferase, multifunctional enzyme, transferase, biosynthetic protein
Biological sourceStreptomyces glaucescens
Total number of polymer chains1
Total formula weight18977.94
Authors
Ames, B.D.,Tsai, S.C. (deposition date: 2007-09-27, release date: 2008-04-22, Last modification date: 2023-08-30)
Primary citationAmes, B.D.,Korman, T.P.,Zhang, W.,Smith, P.,Vu, T.,Tang, Y.,Tsai, S.C.
Crystal structure and functional analysis of tetracenomycin ARO/CYC: implications for cyclization specificity of aromatic polyketides.
Proc.Natl.Acad.Sci.Usa, 105:5349-5354, 2008
Cited by
PubMed: 18388203
DOI: 10.1073/pnas.0709223105
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.95 Å)
Structure validation

217705

数据于2024-03-27公开中

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