2REZ
Tetracenomycin ARO/CYC NaI Structure
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ACT A 155 |
| Chain | Residue |
| A | ARG82 |
| A | GLU84 |
| A | GLY86 |
| A | PRO87 |
| A | PHE88 |
| A | HOH287 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ACT A 156 |
| Chain | Residue |
| A | ARG82 |
| A | HOH286 |
| A | GLU34 |
| A | TRP63 |
| A | TRP65 |
| site_id | AC3 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE IOD A 157 |
| Chain | Residue |
| A | ARG82 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE IOD A 159 |
| Chain | Residue |
| A | ARG149 |
| A | GLY151 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE IOD A 161 |
| Chain | Residue |
| A | ARG147 |
| A | HOH162 |
| A | HOH260 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 129 |
| Details | Region: {"description":"Polyketide cyclase","evidences":[{"evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Proton acceptor; for cyclase activity","evidences":[{"source":"PubMed","id":"22432862","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton donor; for cyclase activity","evidences":[{"source":"PubMed","id":"18388203","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"22432862","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
