2REX

Crystal structure of the effector domain of PLXNB1 bound with Rnd1 GTPase

Summary for 2REX

Related2CLS 2R2O
DescriptorPlexin-B1, Rho-related GTP-binding protein Rho6, UNKNOWN ATOM OR ION, ... (7 entities in total)
Functional Keywordscomplex, structural genomics consortium, sgc, gtpase, gnp, plexin, effector domain, glycoprotein, membrane, phosphorylation, receptor, secreted, transmembrane, cytoskeleton, gtp-binding, lipoprotein, methylation, nucleotide-binding, prenylation, signaling protein-lipoprotein complex, signaling protein/lipoprotein
Biological sourceHomo sapiens (human)
Cellular locationIsoform 1: Cell membrane; Single-pass type I membrane protein. Isoform 2: Secreted. Isoform 3: Secreted O43157
Cell membrane ; Lipid-anchor ; Cytoplasmic side  Q92730
Total number of polymer chains4
Total molecular weight71659.76
Authors
Tong, Y.,Tempel, W.,Shen, L.,Arrowsmith, C.H.,Edwards, A.M.,Sundstrom, M.,Weigelt, J.,Bochkarev, A.,Park, H.,Structural Genomics Consortium (SGC) (deposition date: 2007-09-27, release date: 2007-11-20, Last modification date: 2017-10-25)
Primary citation
Tong, Y.,Tempel, W.,Shen, L.,Arrowsmith, C.H.,Edwards, A.M.,Sundstrom, M.,Weigelt, J.,Bochkarev, A.,Park, H.
Crystal structure of the effector domain of PLXNB1 bound with Rnd1 GTPase.
To be Published,
Experimental method
X-RAY DIFFRACTION (2.3 Å)
NMR Information
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.27450.4%1.9%18.6%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution