2REN

STRUCTURE OF RECOMBINANT HUMAN RENIN, A TARGET FOR CARDIOVASCULAR-ACTIVE DRUGS, AT 2.5 ANGSTROMS RESOLUTION

Summary for 2REN

• Entry DOI: 10.2210/pdb2ren/pdb
• Descriptor: RENIN, 2-acetamido-2-deoxy-beta-D-glucopyranose (2 entities in total)
• Functional Keywords: hydrolase(acid proteinase)
• Biological source: Homo sapiens (human)
• Cellular location: Secreted: P00797
• Total number of polymer chains: 1
• Total formula weight: 37488.22

Authors

Sielecki, A.R.,James, M.N.G. (deposition date: 1992-02-05, release date: 1994-01-31, Last modification date: 2020-07-29)

• Primary citation: Sielecki, A.R.,Hayakawa, K.,Fujinaga, M.,Murphy, M.E.,Fraser, M.,Muir, A.K.,Carilli, C.T.,Lewicki, J.A.,Baxter, J.D.,James, M.N.; Structure of recombinant human renin, a target for cardiovascular-active drugs, at 2.5 A resolution.; Science, 243:1346-1351, 1989; PubMed: 2493678

Experimental method

X-RAY DIFFRACTION (2.5 Å)