2REN

STRUCTURE OF RECOMBINANT HUMAN RENIN, A TARGET FOR CARDIOVASCULAR-ACTIVE DRUGS, AT 2.5 ANGSTROMS RESOLUTION

Experimental procedure

Spacegroup name	I 4
Unit cell lengths	134.080, 134.080, 41.980
Unit cell angles	90.00, 90.00, 90.00

Refinement procedure

Resolution	8.000 - 2.500
R-factor	0.217
RMSD bond length	0.015 *
RMSD bond angle	0.057 *
Phasing software	X-PLOR
Refinement software	GROMOS

Data quality characteristics

	Overall
Low resolution limit [Å]	8.000 *
High resolution limit [Å]	2.500 *
Rmerge	0.480 *
Total number of observations	60512 *
Number of reflections	13343 *

Crystallization Conditions

crystal ID	method	pH	temperature	details
1	Batch method *	4.7 *

Crystallization Reagents in Literatures

ID	crystal ID	solution	reagent name	concentration (unit)	details
1	1	1	PEG	6 (%)
2	1	1		50 (mM)