2RA3

Human cationic trypsin complexed with bovine pancreatic trypsin inhibitor (BPTI)

2RA3 の概要

• エントリーDOI: 10.2210/pdb2ra3/pdb
• 関連するPDBエントリー: 2R9P
• 分子名称: Trypsin-1, Pancreatic trypsin inhibitor, CALCIUM ION, ... (5 entities in total)
• 機能のキーワード: human cationic trypsin, serine protease, bovine pancreatic trypsin inhibitor, bpti, calcium, digestion, disease mutation, hydrolase, metal-binding, secreted, sulfation, zymogen, pharmaceutical, protease inhibitor, serine protease inhibitor, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Secreted, extracellular space: P07477; Secreted: P00974
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 63645.11

構造登録者

Salameh, M.A.,Soares, A.S.,Radisky, E.S. (登録日: 2007-09-14, 公開日: 2007-12-11, 最終更新日: 2023-08-30)

• 主引用文献: Salameh, M.A.,Soares, A.S.,Hockla, A.,Radisky, E.S.; Structural Basis for Accelerated Cleavage of Bovine Pancreatic Trypsin Inhibitor (BPTI) by Human Mesotrypsin.; J.Biol.Chem., 283:4115-4123, 2008; PubMed: 18077447; DOI: 10.1074/jbc.M708268200

実験手法

X-RAY DIFFRACTION (1.46 Å)