2R5N

Crystal structure of transketolase from Escherichia coli in noncovalent complex with acceptor aldose ribose 5-phosphate

2R5N の概要

• エントリーDOI: 10.2210/pdb2r5n/pdb
• 関連するPDBエントリー: 1QGD 2R8O 2R8P
• 分子名称: Transketolase 1, RIBOSE-5-PHOSPHATE, CALCIUM ION, ... (7 entities in total)
• 機能のキーワード: thiamin catalysis, sugar phosphates, acceptor, near attack conformation, cyclic, acyclic, ribose-5-phospate, pyranose, metal-binding, thiamine pyrophosphate, transferase
• 由来する生物種: Escherichia coli
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 148857.22

構造登録者

Parthier, C.,Asztalos, P.,Wille, G.,Tittmann, K. (登録日: 2007-09-04, 公開日: 2007-11-06, 最終更新日: 2023-08-30)

• 主引用文献: Asztalos, P.,Parthier, C.,Golbik, R.,Kleinschmidt, M.,Hubner, G.,Weiss, M.S.,Friedemann, R.,Wille, G.,Tittmann, K.; Strain and Near Attack Conformers in Enzymic Thiamin Catalysis: X-ray Crystallographic Snapshots of Bacterial Transketolase in Covalent Complex with Donor Ketoses Xylulose 5-phosphate and Fructose 6-phosphate, and in Noncovalent Complex with Acceptor Aldose Ribose 5-phosphate.; Biochemistry, 46:12037-12052, 2007; PubMed: 17914867; DOI: 10.1021/bi700844m

実験手法

X-RAY DIFFRACTION (1.6 Å)