2R4R

Crystal structure of the human beta2 adrenoceptor

Summary for 2R4R

• Entry DOI: 10.2210/pdb2r4r/pdb
• Related: 2R4S
• Descriptor: Beta-2 adrenergic receptor, antibody for beta2 adrenoceptor, light chain, antibody for beta2 adrenoceptor, heavy chain (3 entities in total)
• Functional Keywords: transmembrane helix, g-protein coupled receptor, glycoprotein, lipoprotein, palmitate, phosphorylation, receptor, transducer, signaling protein
• Biological source: Homo sapiens (human); More
• Cellular location: Cell membrane; Multi-pass membrane protein: P07550
• Total number of polymer chains: 3
• Total formula weight: 88420.37

Authors

Rasmussen, S.G.F.,Choi, H.J.,Rosenbaum, D.M.,Kobilka, T.S.,Thian, F.S.,Edwards, P.C.,Burghammer, M.,Ratnala, V.R.,Sanishvili, R.,Fischetti, R.F.,Schertler, G.F.,Weis, W.I.,Kobilka, B.K. (deposition date: 2007-08-31, release date: 2007-11-06, Last modification date: 2023-08-30)

• Primary citation: Rasmussen, S.G.F.,Choi, H.J.,Rosenbaum, D.M.,Kobilka, T.S.,Thian, F.S.,Edwards, P.C.,Burghammer, M.,Ratnala, V.R.,Sanishvili, R.,Fischetti, R.F.,Schertler, G.F.,Weis, W.I.,Kobilka, B.K.; Crystal structure of the human beta2 adrenergic G-protein-coupled receptor.; Nature, 450:383-387, 2007; PubMed: 17952055; DOI: 10.1038/nature06325

Experimental method

X-RAY DIFFRACTION (3.4 Å)