2R3A

Methyltransferase domain of human suppressor of variegation 3-9 homolog 2

2R3A の概要

• エントリーDOI: 10.2210/pdb2r3a/pdb
• 分子名称: Histone-lysine N-methyltransferase SUV39H2, ZINC ION, S-ADENOSYLMETHIONINE, ... (5 entities in total)
• 機能のキーワード: histone h3-k9 methyltransferase 2, histone-lysine n-methyltransferase, h3 lysine-9 specific 2, alternative splicing, cell cycle, chromatin regulator, chromosomal protein, differentiation, nucleus, repressor, s-adenosyl-l-methionine, telomere, transcription, transcription regulation, structural genomics, structural genomics consortium, sgc, transferase
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Nucleus (By similarity): Q9H5I1
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 34745.71

構造登録者

Lunin, V.V.,Wu, H.,Zeng, H.,Ren, H.,Loppnau, P.,Weigelt, J.,Sundstrom, M.,Arrowsmith, C.H.,Edwards, A.M.,Bochkarev, A.,Plotnikov, A.N.,Min, J.,Structural Genomics Consortium (SGC) (登録日: 2007-08-29, 公開日: 2007-09-11, 最終更新日: 2023-08-30)

• 主引用文献: Wu, H.,Min, J.,Lunin, V.V.,Antoshenko, T.,Dombrovski, L.,Zeng, H.,Allali-Hassani, A.,Campagna-Slater, V.,Vedadi, M.,Arrowsmith, C.H.,Plotnikov, A.N.,Schapira, M.; Structural biology of human H3K9 methyltransferases; Plos One, 5:e8570-e8570, 2010; PubMed: 20084102; DOI: 10.1371/journal.pone.0008570

実験手法

X-RAY DIFFRACTION (2 Å)