Constitutively zinc-deficient mutant of human superoxide dismutase (SOD), C6A, H80S, H83S, C111S

Summary for 2R27

DescriptorSuperoxide dismutase [Cu-Zn], COPPER (II) ION (3 entities in total)
Functional Keywordsoxidoreductase, beta barrel, cu ion, amyotrophic lateral sclerosis, antioxidant, disease mutation, metal-binding
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm P00441
Total number of polymer chains2
Total molecular weight31790.19
Roberts, B.R.,Getzoff, E.D.,Karplus, P.A.,Beckman, J.S.,Tainer, J.A. (deposition date: 2007-08-24, release date: 2007-12-11, Last modification date: 2011-07-13)
Primary citation
Roberts, B.R.,Tainer, J.A.,Getzoff, E.D.,Malencik, D.A.,Anderson, S.R.,Bomben, V.C.,Meyers, K.R.,Karplus, P.A.,Beckman, J.S.
Structural characterization of zinc-deficient human superoxide dismutase and implications for ALS.
J.Mol.Biol., 373:877-890, 2007
PubMed: 17888947 (PDB entries with the same primary citation)
DOI: 10.1016/j.jmb.2007.07.043
MImport into Mendeley
Experimental method
NMR Information

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.254401.5%3.0%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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