2QUI

Crystal structures of human tryptophanyl-tRNA synthetase in complex with Tryptophanamide and ATP

2QUI の概要

• エントリーDOI: 10.2210/pdb2qui/pdb
• 関連するPDBエントリー: 1O5T 2AKE
• 分子名称: Tryptophanyl-tRNA synthetase, MAGNESIUM ION, L-TRYPTOPHANAMIDE, ... (5 entities in total)
• 機能のキーワード: aminoacyl-trna synthetase, rossmann fold, induced-fit mechnism, atp-binding, cytoplasm, ligase, nucleotide-binding, protein biosynthesis
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Cytoplasm: P23381
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 109058.19

構造登録者

Shen, N.,Ding, J.P. (登録日: 2007-08-05, 公開日: 2008-04-29, 最終更新日: 2023-11-15)

• 主引用文献: Shen, N.,Zhou, M.,Yang, B.,Yu, Y.,Dong, X.,Ding, J.; Catalytic mechanism of the tryptophan activation reaction revealed by crystal structures of human tryptophanyl-tRNA synthetase in different enzymatic states; Nucleic Acids Res., 36:1288-1299, 2008; PubMed: 18180246; DOI: 10.1093/nar/gkm1153

実験手法

X-RAY DIFFRACTION (2.4 Å)