2QQI
Crystal Structure of the b1b2 Domains from Human Neuropilin-1
Summary for 2QQI
Entry DOI | 10.2210/pdb2qqi/pdb |
Related | 2QQJ 2QQK 2QQL 2QQM 2QQN 2QQO |
Descriptor | Neuropilin-1, GLYCEROL (3 entities in total) |
Functional Keywords | vegf receptor, semaphorin receptor, angiogenesis, developmental protein, differentiation, glycoprotein, heparan sulfate, membrane, neurogenesis, proteoglycan, secreted, transmembrane, hormone, signaling protein |
Biological source | Homo sapiens (human) |
Cellular location | Cell membrane; Single-pass type I membrane protein. Isoform 2: Secreted: O14786 |
Total number of polymer chains | 1 |
Total formula weight | 36171.02 |
Authors | Appleton, B.A.,Desmarais, W.,Wiesmann, C. (deposition date: 2007-07-26, release date: 2007-11-20, Last modification date: 2024-10-09) |
Primary citation | Appleton, B.A.,Wu, P.,Maloney, J.,Yin, J.,Liang, W.C.,Stawicki, S.,Mortara, K.,Bowman, K.K.,Elliott, J.M.,Desmarais, W.,Bazan, J.F.,Bagri, A.,Tessier-Lavigne, M.,Koch, A.W.,Wu, Y.,Watts, R.J.,Wiesmann, C. Structural studies of neuropilin/antibody complexes provide insights into semaphorin and VEGF binding Embo J., 26:4902-4912, 2007 Cited by PubMed: 17989695DOI: 10.1038/sj.emboj.7601906 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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