2QQ0

Thymidine Kinase from Thermotoga Maritima in complex with thymidine + AppNHp

Summary for 2QQ0

• Entry DOI: 10.2210/pdb2qq0/pdb
• Related: 2QPO 2QQE
• Descriptor: Thymidine kinase, ZINC ION, MAGNESIUM ION, ... (8 entities in total)
• Functional Keywords: thymidine kinase, tmtk, appnhp, open-conformation, atp-binding, cytoplasm, dna synthesis, nucleotide-binding, transferase
• Biological source: Thermotoga maritima
• Cellular location: Cytoplasm (Potential): Q9WYN2
• Total number of polymer chains: 2
• Total formula weight: 43047.11

Authors

Segura-Pena, D.,Lichter, J.,Trani, M.,Konrad, M.,Lavie, A.,Lutz, S. (deposition date: 2007-07-25, release date: 2007-10-16, Last modification date: 2024-02-21)

• Primary citation: Segura-Pena, D.,Lichter, J.,Trani, M.,Konrad, M.,Lavie, A.,Lutz, S.; Quaternary structure change as a mechanism for the regulation of thymidine kinase 1-like enzymes.; Structure, 15:1555-1566, 2007; PubMed: 18073106; DOI: 10.1016/j.str.2007.09.025

Experimental method

X-RAY DIFFRACTION (1.5 Å)