2QPU

Sugar tongs mutant S378P in complex with acarbose

2QPU の概要

• エントリーDOI: 10.2210/pdb2qpu/pdb
• 関連するPDBエントリー: 1AMY 1HT6 1P6W 1RP8 1RP9 1RPK 2QPS
• 関連するBIRD辞書のPRD_ID: PRD_900022
• 分子名称: Alpha-amylase type A isozyme, 4,6-dideoxy-4-{[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranose, CALCIUM ION, ... (7 entities in total)
• 機能のキーワード: alpha beta 8 barrel, sugar tongs mutant complex, carbohydrate metabolism, germination, glycosidase, hydrolase, metal-binding, secreted
• 由来する生物種: Hordeum vulgare (Barley)
• 細胞内の位置: Secreted, extracellular space: P00693
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 137259.03

構造登録者

Aghajari, N.,Jensen, M.H.,Tranier, S.,Haser, R. (登録日: 2007-07-25, 公開日: 2008-07-01, 最終更新日: 2023-08-30)

• 主引用文献: Bozonnet, S.,Jensen, M.T.,Nielsen, M.M.,Aghajari, N.,Jensen, M.H.,Kramhoft, B.,Willemoes, M.,Tranier, S.,Haser, R.,Svensson, B.; The 'pair of sugar tongs' site on the non-catalytic domain C of barley alpha-amylase participates in substrate binding and activity; Febs J., 274:5055-5067, 2007; PubMed: 17803687; DOI: 10.1111/j.1742-4658.2007.06024.x

実験手法

X-RAY DIFFRACTION (1.7 Å)