1P6W

Crystal structure of barley alpha-amylase isozyme 1 (AMY1) in complex with the substrate analogue, methyl 4I,4II,4III-tri-thiomaltotetraoside (thio-DP4)

Summary for 1P6W

• Entry DOI: 10.2210/pdb1p6w/pdb
• Related: 1AMY 1BG9 1HT6
• Descriptor: PROTEIN (Alpha-amylase type A isozyme), beta-D-glucopyranose-(1-4)-4-thio-beta-D-glucopyranose-(1-4)-4-thio-beta-D-glucopyranose-(1-4)-methyl 4-thio-beta-D-glucopyranoside, alpha-D-glucopyranose-(1-4)-4-thio-beta-D-glucopyranose, ... (5 entities in total)
• Functional Keywords: alpha-amylase, barley, isozyme 1, beta-alpha-barrel, sugar tongs binding site, substrate analogue, hydrolase
• Biological source: Hordeum vulgare
• Cellular location: Secreted, extracellular space: P00693
• Total number of polymer chains: 1
• Total formula weight: 46245.89

Authors

Robert, X.,Haser, R.,Aghajari, N. (deposition date: 2003-04-30, release date: 2003-10-14, Last modification date: 2023-08-16)

• Primary citation: Robert, X.,Haser, R.,Gottschalk, T.E.,Ratajczak, F.,Driguez, H.,Svensson, B.,Aghajari, N.; The structure of barley alpha-amylase isozyme 1 reveals a novel role of domain C in substrate recognition and binding: a pair of sugar tongs; Structure, 11:973-984, 2003; PubMed: 12906828; DOI: 10.1016/S0969-2126(03)00151-5

Experimental method

X-RAY DIFFRACTION (2 Å)