2QN8

Glycogen Phosphorylase b in complex with N-4-nitrobenzoyl-N'-beta-D-glucopyranosyl urea

2QN8 の概要

• エントリーDOI: 10.2210/pdb2qn8/pdb
• 関連するPDBエントリー: 2QLM 2QLN 2QN3 2QN7 2QN9 2QNB
• 分子名称: Glycogen phosphorylase, muscle form, SULFATE ION, PYRIDOXAL-5'-PHOSPHATE, ... (5 entities in total)
• 機能のキーワード: glycogenolysis, type 2 diabetes, allosteric enzyme, carbohydrate metabolism, glycogen metabolism, glycosyltransferase, nucleotide-binding, phosphoprotein, pyridoxal phosphate, transferase
• 由来する生物種: Oryctolagus cuniculus (Rabbit)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 98377.01

構造登録者

Chrysina, E.D.,Tiraidis, C.,Alexacou, K.-M.,Zographos, S.E.,Leonidas, D.D.,Oikonomakos, N.G. (登録日: 2007-07-18, 公開日: 2008-07-22, 最終更新日: 2023-08-30)

• 主引用文献: Nagy, V.,Felf ldi, N.,Praly, J.-P.,Dosca, T.,Gergerly, P.,Chrysina, E.D.,Tiraidis, C.,Kosmopoulou, M.N.,Alexacou, K.-M.,Konstantakaki, M.; N-(4-substituted-benzoyl)-N'-(beta-D-glucopyranosyl)ureas, inhibitors of glycogen phosphorylase: synthesis, kinetic and crystallographic evaluation; To be Published,

実験手法

X-RAY DIFFRACTION (1.9 Å)