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2QL1

Structural Characterization of a Mutated, ADCC-Enhanced Human Fc Fragment

2QL1 の概要
エントリーDOI10.2210/pdb2ql1/pdb
分子名称IGHM protein, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ZINC ION, ... (4 entities in total)
機能のキーワードantibody, adcc, fc fragment, mutation, immune system
由来する生物種Homo sapiens (human)
タンパク質・核酸の鎖数1
化学式量合計27341.92
構造登録者
Oganesyan, V.,Wu, H.,Dall'Acqua, W.F. (登録日: 2007-07-12, 公開日: 2008-04-01, 最終更新日: 2023-08-30)
主引用文献Oganesyan, V.,Damschroder, M.M.,Leach, W.,Wu, H.,Dall'Acqua, W.F.
Structural characterization of a mutated, ADCC-enhanced human Fc fragment
Mol.Immunol., 45:1872-1882, 2008
Cited by
PubMed: 18078997
DOI: 10.1016/j.molimm.2007.10.042
主引用文献が同じPDBエントリー
実験手法
X-RAY DIFFRACTION (2.534 Å)
構造検証レポート
Validation report summary of 2ql1
検証レポート(詳細版)ダウンロードをダウンロード

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件を2024-10-16に公開中

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