2QJ2
A Mechanistic Basis for Converting a Receptor Tyrosine Kinase Agonist to an Antagonist
Summary for 2QJ2
Entry DOI | 10.2210/pdb2qj2/pdb |
Related | 1BHT 1GMN 1GMO 1GP9 1NK1 2HGF 2QJ4 |
Descriptor | Hepatocyte growth factor, SULFATE ION (3 entities in total) |
Functional Keywords | hgf/sf, hormone/growth factor, hormone |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 2 |
Total formula weight | 42702.72 |
Authors | Tolbert, W.D.,Daugherty, J.,Gao, C.-F.,Xe, Q.,Miranti, C.,Gherardi, E.,Vande Woude, G.,Xu, H.E. (deposition date: 2007-07-06, release date: 2007-09-18, Last modification date: 2023-08-30) |
Primary citation | Tolbert, W.D.,Daugherty, J.,Gao, C.,Xie, Q.,Miranti, C.,Gherardi, E.,Vande Woude, G.,Xu, H.E. A mechanistic basis for converting a receptor tyrosine kinase agonist to an antagonist Proc.Natl.Acad.Sci.Usa, 104:14592-14597, 2007 Cited by PubMed: 17804794DOI: 10.1073/pnas.0704290104 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.81 Å) |
Structure validation
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