2QFA

Crystal structure of a Survivin-Borealin-INCENP core complex

Summary for 2QFA

Entry DOI	10.2210/pdb2qfa/pdb
Descriptor	Baculoviral IAP repeat-containing protein 5, Borealin, Inner centromere protein, ... (6 entities in total)
Functional Keywords	three-helical-bundle, long helix, protein complex, alternative splicing, apoptosis, cell cycle, cell division, centromere, chromosomal protein, cytoplasm, metal-binding, mitosis, nucleus, phosphorylation, polymorphism, protease inhibitor, thiol protease inhibitor, zinc, coiled coil, microtubule, cell cycle-cell cycle-cell cycle complex, cell cycle/cell cycle/cell cycle
Biological source	Homo sapiens (human) More
Cellular location	Cytoplasm: O15392 Nucleus, nucleolus: Q53HL2 Chromosome, centromere: Q9NQS7
Total number of polymer chains	3
Total formula weight	29870.69
Authors	Jeyaprakash, A.A.,Klein, U.R.,Lindner, D.,Ebert, J.,Nigg, E.A.,Conti, E. (deposition date: 2007-06-27, release date: 2007-11-06, Last modification date: 2024-02-21)
Primary citation	Jeyaprakash, A.A.,Klein, U.R.,Lindner, D.,Ebert, J.,Nigg, E.A.,Conti, E. Structure of a Survivin-Borealin-INCENP Core Complex Reveals How Chromosomal Passengers Travel Together. Cell(Cambridge,Mass.), 131:271-285, 2007 Cited by PubMed: 17956729 DOI: 10.1016/j.cell.2007.07.045 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.4 Å)

Structure validation