2QFA

Crystal structure of a Survivin-Borealin-INCENP core complex

2QFA の概要

• エントリーDOI: 10.2210/pdb2qfa/pdb
• 分子名称: Baculoviral IAP repeat-containing protein 5, Borealin, Inner centromere protein, ... (6 entities in total)
• 機能のキーワード: three-helical-bundle, long helix, protein complex, alternative splicing, apoptosis, cell cycle, cell division, centromere, chromosomal protein, cytoplasm, metal-binding, mitosis, nucleus, phosphorylation, polymorphism, protease inhibitor, thiol protease inhibitor, zinc, coiled coil, microtubule, cell cycle-cell cycle-cell cycle complex, cell cycle/cell cycle/cell cycle
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Cytoplasm: O15392; Nucleus, nucleolus: Q53HL2; Chromosome, centromere: Q9NQS7
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 29870.69

構造登録者

Jeyaprakash, A.A.,Klein, U.R.,Lindner, D.,Ebert, J.,Nigg, E.A.,Conti, E. (登録日: 2007-06-27, 公開日: 2007-11-06, 最終更新日: 2024-02-21)

• 主引用文献: Jeyaprakash, A.A.,Klein, U.R.,Lindner, D.,Ebert, J.,Nigg, E.A.,Conti, E.; Structure of a Survivin-Borealin-INCENP Core Complex Reveals How Chromosomal Passengers Travel Together.; Cell(Cambridge,Mass.), 131:271-285, 2007; PubMed: 17956729; DOI: 10.1016/j.cell.2007.07.045

実験手法

X-RAY DIFFRACTION (1.4 Å)