2Q8C

Crystal structure of JMJD2A in ternary complex with an histone H3K9me3 peptide and 2-oxoglutarate

Summary for 2Q8C

• Entry DOI: 10.2210/pdb2q8c/pdb
• Related: 2Q8D 2Q8E
• Descriptor: JmjC domain-containing histone demethylation protein 3A, HISTONE 3 PEPTIDE, NICKEL (II) ION, ... (6 entities in total)
• Functional Keywords: histone demethylase, hydroxylase, jumonji, oxidoreductase
• Biological source: Homo sapiens (human); More
• Cellular location: Nucleus : O75164
• Total number of polymer chains: 4
• Total formula weight: 85483.16

Authors

Couture, J.-F.,Collazo, E.,Ortiz-Tello, P.,Brunzelle, J.S.,Trievel, R.C. (deposition date: 2007-06-10, release date: 2007-07-03, Last modification date: 2023-08-30)

• Primary citation: Couture, J.F.,Collazo, E.,Ortiz-Tello, P.A.,Brunzelle, J.S.,Trievel, R.C.; Specificity and mechanism of JMJD2A, a trimethyllysine-specific histone demethylase.; Nat.Struct.Mol.Biol., 14:689-695, 2007; PubMed: 17589523; DOI: 10.1038/nsmb1273

Experimental method

X-RAY DIFFRACTION (2.047 Å)