Summary for 2Q80
| Entry DOI | 10.2210/pdb2q80/pdb |
| Descriptor | Geranylgeranyl pyrophosphate synthetase, MAGNESIUM ION, GERANYLGERANYL DIPHOSPHATE, ... (4 entities in total) |
| Functional Keywords | isoprenoid pathway, isopentenyl transferase, structural genomics, structural genomics consortium, sgc, transferase |
| Biological source | Homo sapiens (human) |
| Cellular location | Cytoplasm: O95749 |
| Total number of polymer chains | 6 |
| Total formula weight | 213011.78 |
| Authors | Kavanagh, K.L.,Dunford, J.E.,Bunkoczi, G.,Smee, C.,von Delft, F.,Arrowsmith, C.,Weigelt, J.,Edwards, A.,Sundstrom, M.,Oppermann, U.,Structural Genomics Consortium (SGC) (deposition date: 2007-06-08, release date: 2007-06-19, Last modification date: 2024-04-03) |
| Primary citation | Kavanagh, K.L.,Dunford, J.E.,Bunkoczi, G.,Russell, R.G.,Oppermann, U. The crystal structure of human geranylgeranyl pyrophosphate synthase reveals a novel hexameric arrangement and inhibitory product binding J.Biol.Chem., 281:22004-22012, 2006 Cited by PubMed: 16698791DOI: 10.1074/jbc.M602603200 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
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