2Q5L

X-ray structure of phenylpyruvate decarboxylase in complex with 2-(1-hydroxyethyl)-3-deaza-ThDP

Summary for 2Q5L

Entry DOI	10.2210/pdb2q5l/pdb
Related	2Q5J 2Q5O 2Q5Q 2nxw
Descriptor	PHENYLPYRUVATE DECARBOXYLASE, MAGNESIUM ION, CHLORIDE ION, ... (7 entities in total)
Functional Keywords	thiamine diphosphate, asymmetric dimer of dimers, open active site loop, covalent intermediate analogue, lyase
Biological source	Azospirillum brasilense
Total number of polymer chains	2
Total formula weight	122826.90
Authors	Versees, W.,Spaepen, S.,Wood, M.D.,Leeper, F.J.,Vanderleyden, J.,Steyaert, J. (deposition date: 2007-06-01, release date: 2007-10-23, Last modification date: 2023-08-30)
Primary citation	Versees, W.,Spaepen, S.,Wood, M.D.,Leeper, F.J.,Vanderleyden, J.,Steyaert, J. Molecular mechanism of allosteric substrate activation in a thiamine diphosphate-dependent decarboxylase. J.Biol.Chem., 282:35269-35278, 2007 Cited by PubMed: 17905741 DOI: 10.1074/jbc.M706048200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.85 Å)

Structure validation