2PZG

Minimal human CFTR first nucleotide binding domain as a monomer

Summary for 2PZG

• Entry DOI: 10.2210/pdb2pzg/pdb
• Related: 1L2T 1Q12 1R0Z 1R10 1XEF 1XMI 1XMJ 2BB0 2BBS 2BBT 2HYD 2IXE 2PZE 2PZF
• Descriptor: Cystic fibrosis transmembrane conductance regulator, MAGNESIUM ION, ADENOSINE-5'-TRIPHOSPHATE, ... (5 entities in total)
• Functional Keywords: nbd, abc transporter, cftr, hydrolase
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 55471.50

Authors

Atwell, S.,Conners, K.,Emtage, S.,Gheyi, T.,Glenn, N.R.,Hendle, J.,Lewis, H.A.,Lu, F.,Rodgers, L.A.,Romero, R.,Sauder, J.M.,Smith, D.,Tien, H.,Wasserman, S.R.,Zhao, X. (deposition date: 2007-05-18, release date: 2007-10-09, Last modification date: 2023-08-30)

• Primary citation: Atwell, S.,Brouillette, C.G.,Conners, K.,Emtage, S.,Gheyi, T.,Guggino, W.B.,Hendle, J.,Hunt, J.F.,Lewis, H.A.,Lu, F.,Protasevich, I.I.,Rodgers, L.A.,Romero, R.,Wasserman, S.R.,Weber, P.C.,Wetmore, D.,Zhang, F.F.,Zhao, X.; Structures of a minimal human CFTR first nucleotide-binding domain as a monomer, head-to-tail homodimer, and pathogenic mutant.; Protein Eng.Des.Sel., 23:375-384, 2010; PubMed: 20150177; DOI: 10.1093/protein/gzq004

Experimental method

X-RAY DIFFRACTION (1.8 Å)