2PYI
Crystal structure of Glycogen Phosphorylase in complex with glucosyl triazoleacetamide
Summary for 2PYI
Entry DOI | 10.2210/pdb2pyi/pdb |
Related | 2PYD |
Descriptor | Glycogen phosphorylase, muscle form, N-[(4-PHENYL-1H-1,2,3-TRIAZOL-1-YL)ACETYL]-BETA-D-GLUCOPYRANOSYLAMINE, DIMETHYL SULFOXIDE, ... (4 entities in total) |
Functional Keywords | glycogenolysis, inhibition, type 2 diabetes, transferase |
Biological source | Oryctolagus cuniculus (rabbit) |
Total number of polymer chains | 1 |
Total formula weight | 98796.20 |
Authors | Alexacou, K.M.,Tiraidis, C.,Zographos, S.E.,Chrysina, E.D.,Hayes, J.,Oikonomakos, N.G. (deposition date: 2007-05-16, release date: 2008-04-01, Last modification date: 2023-11-15) |
Primary citation | Alexacou, K.M.,Hayes, J.M.,Tiraidis, C.,Zographos, S.E.,Leonidas, D.D.,Chrysina, E.D.,Archontis, G.,Oikonomakos, N.G.,Paul, J.V.,Varghese, B.,Loganathan, D. Crystallographic and computational studies on 4-phenyl-N-(beta-D-glucopyranosyl)-1H-1,2,3-triazole-1-acetamide, an inhibitor of glycogen phosphorylase: Comparison with alpha-D-glucose, N-acetyl-beta-D-glucopyranosylamine and N-benzoyl-N'-beta-D-glucopyranosyl urea binding. Proteins, 71:1307-1323, 2007 Cited by PubMed: 18041758DOI: 10.1002/prot.21837 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.88 Å) |
Structure validation
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