2PXR

Crystal Structure of HIV-1 CA146 in the Presence of CAP-1

Summary for 2PXR

• Entry DOI: 10.2210/pdb2pxr/pdb
• Related: 2JPR 2PWM 2PWO
• Descriptor: Gag-Pol polyprotein (Pr160Gag-Pol), CHLORIDE ION, ZINC ION, ... (4 entities in total)
• Functional Keywords: viral capsid, hiv-1, anti-viral, small molecule inhibition, viral protein
• Biological source: Human immunodeficiency virus 1
• Cellular location: Matrix protein p17: Virion (Potential). Capsid protein p24: Virion (Potential). Nucleocapsid protein p7: Virion (Potential). Reverse transcriptase/ribonuclease H: Virion (Potential). Integrase: Virion (Potential): P12497
• Total number of polymer chains: 1
• Total formula weight: 16370.84

Authors

Kelly, B.N. (deposition date: 2007-05-14, release date: 2007-09-25, Last modification date: 2024-02-21)

• Primary citation: Kelly, B.N.,Kyere, S.,Kinde, I.,Tang, C.,Howard, B.R.,Robinson, H.,Sundquist, W.I.,Summers, M.F.,Hill, C.P.; Structure of the Antiviral Assembly Inhibitor CAP-1 Complex with the HIV-1 CA Protein.; J.Mol.Biol., 373:355-366, 2007; PubMed: 17826792; DOI: 10.1016/j.jmb.2007.07.070

Experimental method

X-RAY DIFFRACTION (1.5 Å)