2PW8

Crystal structure of sulfo-hirudin complexed to thrombin

Summary for 2PW8

Entry DOI	10.2210/pdb2pw8/pdb
Related	4HTC
Descriptor	Thrombin light chain, Thrombin heavy chain, Hirudin variant-1, ... (6 entities in total)
Functional Keywords	thrombin, hirudin, sulfotyrosine, hydrolase
Biological source	Hirudo medicinalis (medicinal leech) More
Cellular location	Secreted, extracellular space: P00734 P00734 Secreted: P01050
Total number of polymer chains	3
Total formula weight	39990.98
Authors	Liu, C.C.,Brustad, E.,Liu, W.,Schultz, P.G. (deposition date: 2007-05-10, release date: 2007-08-21, Last modification date: 2024-11-20)
Primary citation	Liu, C.C.,Brustad, E.,Liu, W.,Schultz, P.G. Crystal structure of a biosynthetic sulfo-hirudin complexed to thrombin. J.Am.Chem.Soc., 129:10648-10649, 2007 Cited by PubMed: 17685615 DOI: 10.1021/ja0735002 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.84 Å)

Structure validation