2PRG

LIGAND-BINDING DOMAIN OF THE HUMAN PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA

2PRG の概要

• エントリーDOI: 10.2210/pdb2prg/pdb
• 分子名称: PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA, NUCLEAR RECEPTOR COACTIVATOR SRC-1, 2,4-THIAZOLIDIINEDIONE, 5-[[4-[2-(METHYL-2-PYRIDINYLAMINO)ETHOXY]PHENYL]METHYL]-(9CL), ... (4 entities in total)
• 機能のキーワード: complex (thiazolidinedione-receptor), ligand-binding domain, nuclear receptor, apo, transcription factor, orphan receptor, complex (thiazolidinedione-receptor) complex, complex (thiazolidinedione/receptor)
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 72105.12

構造登録者

Nolte, R.T.,Wisely, G.B.,Milburn, M.V. (登録日: 1998-08-14, 公開日: 1999-07-19, 最終更新日: 2023-08-09)

• 主引用文献: Nolte, R.T.,Wisely, G.B.,Westin, S.,Cobb, J.E.,Lambert, M.H.,Kurokawa, R.,Rosenfeld, M.G.,Willson, T.M.,Glass, C.K.,Milburn, M.V.; Ligand binding and co-activator assembly of the peroxisome proliferator-activated receptor-gamma.; Nature, 395:137-143, 1998; PubMed: 9744270; DOI: 10.1038/25931

実験手法

X-RAY DIFFRACTION (2.3 Å)