2POP

The Crystal Structure of TAB1 and BIR1 complex

Summary for 2POP

• Entry DOI: 10.2210/pdb2pop/pdb
• Related: 2POI 2POM
• Descriptor: Mitogen-activated protein kinase kinase kinase 7-interacting protein 1, Baculoviral IAP repeat-containing protein 4, ZINC ION (3 entities in total)
• Functional Keywords: zinc finger, pp2c-like domain, bir domain, signaling protein-apoptosis complex, signaling protein/apoptosis
• Biological source: Homo sapiens (Human); More
• Cellular location: Cytoplasm: P98170
• Total number of polymer chains: 4
• Total formula weight: 98585.15

Authors

Lin, S.C. (deposition date: 2007-04-27, release date: 2007-07-03, Last modification date: 2023-08-30)

• Primary citation: Lu, M.,Lin, S.C.,Huang, Y.,Kang, Y.J.,Rich, R.,Lo, Y.C.,Myszka, D.,Han, J.,Wu, H.; XIAP Induces NF-kappaB Activation via the BIR1/TAB1 Interaction and BIR1 Dimerization.; Mol.Cell, 26:689-702, 2007; PubMed: 17560374; DOI: 10.1016/j.molcel.2007.05.006

Experimental method

X-RAY DIFFRACTION (3.1 Å)