2POP

The Crystal Structure of TAB1 and BIR1 complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C (A, C)	Mitogen-activated protein kinase kinase kinase 7-interacting protein 1	polymer	353	38615.4	2	UniProt (Q15750) Pfam (PF00481)	Homo sapiens (Human)	TGF-beta-activated kinase 1 and MAP3K7-binding protein 1,TGF-beta-activated kinase 1-binding protein 1,TAK1-binding protein 1
2	B, D (B, D)	Baculoviral IAP repeat-containing protein 4	polymer	95	10611.8	2	UniProt (P98170) Pfam (PF00653)	Homo sapiens (Human)	E3 ubiquitin-protein ligase XIAP,IAP-like protein,hILP,Inhibitor of apoptosis protein 3,hIAP3,RING-type E3 ubiquitin transferase XIAP,X-linked inhibitor of apoptosis protein,X-linked IAP
3	E, F (B, D)	ZINC ION	non-polymer		65.4	2	Chemie (ZN)

Sequence modifications

A, C: 1 - 132 (UniProt: Q15750)

PDB	External Database	Details
Gly -1	-	expression tag
Ser 0	-	expression tag

A, C: 152 - 370 (UniProt: Q15750)
B, D: 1010 - 1100 (UniProt: P98170)

PDB	External Database	Details
Gly 1006	-	expression tag
Ser 1007	-	expression tag
His 1008	-	expression tag
Met 1009	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	98454.3
Non-Polymers*	Number of molecules	2
	Total formula weight	130.8
All*	Total formula weight	98585.2

*Water molecules are not included.