2PIZ

CRYSTAL STRUCTURE OF ACTIVATED PORCINE PANCREATIC CARBOXYPEPTIDASE B 2-(3-Guanidino-phenyl)-3-[hydroxy-(3-phenyl-propyl)-phosphinoyl]-propionic acid COMPLEX

Summary for 2PIZ

Entry DOI	10.2210/pdb2piz/pdb
Related	1Z5R 1ZG7 1ZG8 1ZG9 2PIY 2PJ0 2PJ1 2PJ2 2PJ3 2PJ4 2PJ5 2PJ6 2PJ7 2PJ8 2PJ9 2PJA 2PJB 2PJC
Descriptor	Carboxypeptidase B, ZINC ION, (2S)-2-(3-{[AMINO(IMINO)METHYL]AMINO}PHENYL)-3-[(S)-HYDROXY(3-PHENYLPROPYL)PHOSPHORYL]PROPANOIC ACID, ... (4 entities in total)
Functional Keywords	carboxypeptidase b, exopeptidase, phosphinate based inhibitors, hydrolase
Biological source	Sus scrofa (pig)
Cellular location	Secreted: P09955
Total number of polymer chains	3
Total formula weight	105583.96
Authors	Adler, M.,Whitlow, M. (deposition date: 2007-04-15, release date: 2008-01-22, Last modification date: 2023-08-30)
Primary citation	Adler, M.,Buckman, B.,Bryant, J.,Chang, Z.,Chu, K.,Emayan, K.,Hrvatin, P.,Islam, I.,Morser, J.,Sukovich, D.,West, C.,Yuan, S.,Whitlow, M. Structures of potent selective peptide mimetics bound to carboxypeptidase B. Acta Crystallogr.,Sect.D, 64:149-157, 2008 Cited by PubMed: 18219114 DOI: 10.1107/S0907444907057228 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.6 Å)

Structure validation