2PG8

Crystal structure of R254K mutanat of DpgC with bound substrate analog

Summary for 2PG8

• Entry DOI: 10.2210/pdb2pg8/pdb
• Related: 2NP9
• Descriptor: DpgC, [(2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-4-HYDROXY-3-(PHOSPHONOOXY)TETRAHYDROFURAN-2-YL]METHYL (3R)-4-({3-[(2-{[(3,5-DIHYDROXYPHENYL)ACETYL]AMINO}ETHYL)AMINO]-3-OXOPROPYL}AMINO)-3-HYDROXY-2,2-DIMETHYL-4-OXOBUTYL DIHYDROGEN DIPHOSPHATE, OXYGEN MOLECULE, ... (4 entities in total)
• Functional Keywords: protein-ligand complex, ligand binding protein
• Biological source: Streptomyces toyocaensis
• Total number of polymer chains: 3
• Total formula weight: 140734.37

Authors

Fielding, E.N. (deposition date: 2007-04-09, release date: 2008-01-22, Last modification date: 2023-08-30)

• Primary citation: Fielding, E.N.,Widboom, P.F.,Bruner, S.D.; Substrate Recognition and Catalysis by the Cofactor-Independent Dioxygenase DpgC.; Biochemistry, 46:13994-14000, 2007; PubMed: 18004875; DOI: 10.1021/bi701148b

Experimental method

X-RAY DIFFRACTION (3 Å)