2PG8
Crystal structure of R254K mutanat of DpgC with bound substrate analog
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | DpgC | polymer | 417 | 45989.5 | 3 | UniProt (Q8KLK7) Pfam (PF00378) | Streptomyces toyocaensis | |
| 2 | D, F, G (A, B, C) | [(2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-4-HYDROXY-3-(PHOSPHONOOXY)TETRAHYDROFURAN-2-YL]METHYL (3R)-4-({3-[(2-{[(3,5-DIHYDROXYPHENYL)ACETYL]AMINO}ETHYL)AMINO]-3-OXOPROPYL}AMINO)-3-HYDROXY-2,2-DIMETHYL-4-OXOBUTYL DIHYDROGEN DIPHOSPHATE | non-polymer | 900.6 | 3 | Chemie (YE1) | |||
| 3 | E, H (A, C) | OXYGEN MOLECULE | non-polymer | 32.0 | 2 | Chemie (OXY) | |||
| 4 | I, J, K (A, B, C) | water | water | 18.0 | 123 | Chemie (HOH) |
Sequence modifications
A, B, C: 10 - 426 (UniProt: Q8KLK7)
| PDB | External Database | Details |
|---|---|---|
| Lys 254 | Arg 254 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 137968.5 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 2765.8 | |
| All* | Total formula weight | 140734.4 |
