2PE4

Structure of Human Hyaluronidase 1, a Hyaluronan Hydrolyzing Enzyme Involved in Tumor Growth and Angiogenesis

2PE4 の概要

• エントリーDOI: 10.2210/pdb2pe4/pdb
• 分子名称: Hyaluronidase-1, alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total)
• 機能のキーワード: hyaluronidase, hyaluronan, egf-like domain, hydrolase
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Secreted : Q12794
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 49417.18

構造登録者

Chao, K.L.,Herzberg, O. (登録日: 2007-04-02, 公開日: 2007-06-12, 最終更新日: 2023-08-30)

• 主引用文献: Chao, K.L.,Muthukumar, L.,Herzberg, O.; Structure of Human Hyaluronidase-1, a Hyaluronan Hydrolyzing Enzyme Involved in Tumor Growth and Angiogenesis; Biochemistry, 46:6911-6920, 2007; PubMed: 17503783; DOI: 10.1021/bi700382g

実験手法

X-RAY DIFFRACTION (2 Å)