2PD6

Structure of human hydroxysteroid dehydrogenase type 8, HSD17B8

Summary for 2PD6

• Entry DOI: 10.2210/pdb2pd6/pdb
• Descriptor: Estradiol 17-beta-dehydrogenase 8, NICOTINAMIDE-ADENINE-DINUCLEOTIDE (3 entities in total)
• Functional Keywords: short-chain dehydrogenase/reductase, steroid metabolism, lipid metabolism, structural genomics, structural genomics consortium, sgc, oxidoreductase
• Biological source: Homo sapiens (human)
• Cellular location: Mitochondrion matrix: Q92506
• Total number of polymer chains: 4
• Total formula weight: 112518.59

Authors

Turnbull, A.P.,Salah, E.,Gileadi, O.,Savitsky, P.,Guo, K.,Bunkoczi, G.,Pike, A.C.W.,Ugochukwu, E.,Umeano, C.,von Delft, F.,Weigelt, J.,Arrowsmith, C.H.,Sundstrom, M.,Edwards, A.,Oppermann, U.,Structural Genomics Consortium (SGC) (deposition date: 2007-03-31, release date: 2007-05-08, Last modification date: 2023-08-30)

• Primary citation: Turnbull, A.P.,Salah, E.,Gileadi, O.,Savitsky, P.,Guo, K.,Bunkoczi, G.,Pike, A.C.W.,Ugochukwu, E.,Umeano, C.,von Delft, F.,Weigelt, J.,Arrowsmith, C.H.,Sundstrom, M.,Edwards, A.,Oppermann, U.,Structural Genomics Consortium (SGC); Structure of human hydroxysteroid dehydrogenase type 8, HSD17B8; To be Published,

Experimental method

X-RAY DIFFRACTION (2 Å)