2P6B

Crystal Structure of Human Calcineurin in Complex with PVIVIT Peptide

Summary for 2P6B

Entry DOI	10.2210/pdb2p6b/pdb
Descriptor	PVIVIT 14-mer Peptide, Calmodulin-dependent calcineurin A subunit alpha isoform, Calcineurin subunit B isoform 1, ... (8 entities in total)
Functional Keywords	beta-sheet augmentation; protein-peptide complex, hydrolase-hydrolase regulator complex, hydrolase/hydrolase regulator
Biological source	Homo sapiens (human) More
Total number of polymer chains	5
Total formula weight	125727.47
Authors	Li, H.,Zhang, L.,Rao, A.,Harrison, S.C.,Hogan, P.G. (deposition date: 2007-03-16, release date: 2007-06-05, Last modification date: 2023-08-30)
Primary citation	Li, H.,Zhang, L.,Rao, A.,Harrison, S.C.,Hogan, P.G. Structure of calcineurin in complex with PVIVIT peptide: Portrait of a low-affinity signalling interaction J.Mol.Biol., 369:1296-1306, 2007 Cited by PubMed: 17498738 DOI: 10.1016/j.jmb.2007.04.032 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation