2P2A
X-ray structure of the GluR2 ligand binding core (S1S2J) in complex with 2-Bn-tet-AMPA at 2.26A resolution
Summary for 2P2A
Entry DOI | 10.2210/pdb2p2a/pdb |
Related | 1FTJ 1FTM 1M5B |
Descriptor | Glutamate receptor 2, SULFATE ION, GLUTAMIC ACID, ... (5 entities in total) |
Functional Keywords | ionotropic glutamate receptor glur2, ligand-binding core, agonist complex, membrane protein |
Biological source | Rattus norvegicus (Norway rat) More |
Cellular location | Cell membrane; Multi-pass membrane protein: P19491 |
Total number of polymer chains | 2 |
Total formula weight | 59208.98 |
Authors | Frydenvang, K.,Kastrup, J.S.,Gajhede, M. (deposition date: 2007-03-07, release date: 2007-06-19, Last modification date: 2023-09-20) |
Primary citation | Vogensen, S.B.,Frydenvang, K.,Greenwood, J.R.,Postorino, G.,Nielsen, B.,Pickering, D.S.,Ebert, B.,Bolcho, U.,Egebjerg, J.,Gajhede, M.,Kastrup, J.S.,Johansen, T.N.,Clausen, R.P.,Krogsgaard-Larsen, P. A tetrazolyl-substituted subtype-selective AMPA receptor agonist. J.Med.Chem., 50:2408-2414, 2007 Cited by PubMed: 17455929DOI: 10.1021/jm061439q PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.26 Å) |
Structure validation
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