2P2A
X-ray structure of the GluR2 ligand binding core (S1S2J) in complex with 2-Bn-tet-AMPA at 2.26A resolution
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Glutamate receptor 2 | polymer | 263 | 29221.7 | 2 | UniProt (P19491) Pfam (PF10613) Pfam (PF00060) | Rattus norvegicus (Norway rat) | GluR-2, GluR-B, GluR-K2, Glutamate receptor ionotropic, AMPA 2, AMPA-selective glutamate receptor 2 |
| 2 | C, D, F (A, B) | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 3 | E (A) | GLUTAMIC ACID | non-polymer | 147.1 | 1 | Chemie (GLU) | |||
| 4 | G (B) | 2-AMINO-3-[3-HYDROXY-5-(2-BENZYL-2H-5-TETRAZOLYL)-4-ISOXAZOLYL]-PROPIONIC ACID | non-polymer | 330.3 | 1 | Chemie (MP9) | |||
| 5 | H, I (A, B) | water | water | 18.0 | 410 | Chemie (HOH) |
Sequence modifications
A, B: 0 - 114 (UniProt: P19491)
A, B: 117 - 260 (UniProt: P19491)
| PDB | External Database | Details |
|---|---|---|
| Gly -2 | - | cloning artifact |
| Ala -1 | - | cloning artifact |
| PDB | External Database | Details |
|---|---|---|
| Gly 115 | - | linker |
| Thr 116 | - | linker |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 58443.4 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 765.6 | |
| All* | Total formula weight | 59209.0 |
