2P0C
Catalytic Domain of the Proto-oncogene Tyrosine-protein Kinase MER
Summary for 2P0C
Entry DOI | 10.2210/pdb2p0c/pdb |
Descriptor | Proto-oncogene tyrosine-protein kinase MER, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... (5 entities in total) |
Functional Keywords | atp-binding, disease mutation, glycoprotein, kinase, nucleotide-binding, phosphorylation, proto-oncogene, receptor, retinitis pigmentosa, sensory transduction, transferase, tyrosine-protein kinase, vision, structural genomics, structural genomics consortium, sgc |
Biological source | Homo sapiens (human) |
Cellular location | Membrane; Single-pass type I membrane protein (By similarity): Q12866 |
Total number of polymer chains | 2 |
Total formula weight | 72942.31 |
Authors | Walker, J.R.,Huang, X.,Finerty Jr., P.J.,Weigelt, J.,Sundstrom, M.,Arrowsmith, C.H.,Edwards, A.M.,Bochkarev, A.,Dhe-Paganon, S.,Structural Genomics Consortium (SGC) (deposition date: 2007-02-28, release date: 2007-05-08, Last modification date: 2023-08-30) |
Primary citation | Huang, X.,Finerty, P.,Walker, J.R.,Butler-Cole, C.,Vedadi, M.,Schapira, M.,Parker, S.A.,Turk, B.E.,Thompson, D.A.,Dhe-Paganon, S. Structural insights into the inhibited states of the Mer receptor tyrosine kinase. J.Struct.Biol., 165:88-96, 2009 Cited by PubMed: 19028587DOI: 10.1016/j.jsb.2008.10.003 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
Download full validation report