Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004672 | molecular_function | protein kinase activity |
| A | 0004713 | molecular_function | protein tyrosine kinase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006468 | biological_process | protein phosphorylation |
| B | 0004672 | molecular_function | protein kinase activity |
| B | 0004713 | molecular_function | protein tyrosine kinase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0006468 | biological_process | protein phosphorylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE MG A 4 |
| Chain | Residue |
| A | ANP1 |
| A | ASN728 |
| A | ASP741 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MG B 5 |
| Chain | Residue |
| B | ANP2 |
| B | HOH129 |
| B | ASN728 |
| B | ASP741 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE MG B 6 |
| Chain | Residue |
| B | GLU712 |
| B | ASN716 |
| site_id | AC4 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE ANP A 1 |
| Chain | Residue |
| A | MG4 |
| A | HOH82 |
| A | HOH84 |
| A | HOH113 |
| A | HOH121 |
| A | HOH141 |
| A | LEU593 |
| A | GLY594 |
| A | VAL601 |
| A | ALA617 |
| A | PRO672 |
| A | PHE673 |
| A | MET674 |
| A | ASP723 |
| A | ARG727 |
| A | ASN728 |
| A | MET730 |
| A | ASP741 |
| site_id | AC5 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE ANP B 2 |
| Chain | Residue |
| B | MG5 |
| B | HOH51 |
| B | HOH66 |
| B | HOH83 |
| B | HOH129 |
| B | HOH156 |
| B | HOH163 |
| B | HOH170 |
| B | LEU593 |
| B | VAL601 |
| B | ALA617 |
| B | PRO672 |
| B | PHE673 |
| B | MET674 |
| B | ASP678 |
| B | ARG727 |
| B | ASP741 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE BME A 3 |
| Chain | Residue |
| A | LEU697 |
| A | ALA794 |
| A | ARG796 |
| A | CYS825 |
| A | LEU829 |
Functional Information from PROSITE/UniProt
| site_id | PS00107 |
| Number of Residues | 27 |
| Details | PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. LGEGEFGSVMeGnlkqedgtslk.......VAVK |
| Chain | Residue | Details |
| A | LEU593-LYS619 | |
| site_id | PS00109 |
| Number of Residues | 13 |
| Details | PROTEIN_KINASE_TYR Tyrosine protein kinases specific active-site signature. FLHrDLAARNCML |
| Chain | Residue | Details |
| A | PHE719-LEU731 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"},{"source":"PROSITE-ProRule","id":"PRU10028","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"}]} |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1ir3 |
| Chain | Residue | Details |
| A | ARG727 | |
| A | ASP723 | |
| site_id | CSA2 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1ir3 |
| Chain | Residue | Details |
| B | ARG727 | |
| B | ASP723 | |
| site_id | CSA3 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1ir3 |
| Chain | Residue | Details |
| A | ALA725 | |
| A | ASP723 | |
| site_id | CSA4 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1ir3 |
| Chain | Residue | Details |
| B | ALA725 | |
| B | ASP723 | |
| site_id | CSA5 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1ir3 |
| Chain | Residue | Details |
| A | ALA725 | |
| A | ASN728 | |
| A | ASP723 | |
| site_id | CSA6 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1ir3 |
| Chain | Residue | Details |
| B | ALA725 | |
| B | ASN728 | |
| B | ASP723 | |
