2P0C
Catalytic Domain of the Proto-oncogene Tyrosine-protein Kinase MER
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Proto-oncogene tyrosine-protein kinase MER | polymer | 313 | 35889.4 | 2 | UniProt (Q12866) Pfam (PF07714) | Homo sapiens (human) | C-mer, Receptor tyrosine kinase MerTK |
| 2 | C, F, G (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 3 | Chemie (MG) | |||
| 3 | D, H (A, B) | PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | non-polymer | 506.2 | 2 | Chemie (ANP) | |||
| 4 | E (A) | BETA-MERCAPTOETHANOL | non-polymer | 78.1 | 1 | Chemie (BME) | |||
| 5 | I, J (A, B) | water | water | 18.0 | 164 | Chemie (HOH) |
Sequence modifications
A, B: 570 - 864 (UniProt: Q12866)
| PDB | External Database | Details |
|---|---|---|
| Met 552 | - | cloning artifact |
| Gly 553 | - | cloning artifact |
| Ser 554 | - | cloning artifact |
| Ser 555 | - | cloning artifact |
| His 556 | - | cloning artifact |
| His 557 | - | cloning artifact |
| His 558 | - | cloning artifact |
| His 559 | - | cloning artifact |
| His 560 | - | cloning artifact |
| His 561 | - | cloning artifact |
| Ser 562 | - | cloning artifact |
| Ser 563 | - | cloning artifact |
| Gly 564 | - | cloning artifact |
| Leu 565 | - | cloning artifact |
| Val 566 | - | cloning artifact |
| Pro 567 | - | cloning artifact |
| Arg 568 | - | cloning artifact |
| Gly 569 | - | cloning artifact |
| Gln 628 | His 628 | conflict |
| Ala 794 | Arg 794 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 71778.9 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1163.4 | |
| All* | Total formula weight | 72942.3 |
