2OXU
Uninhibited form of human MMP-12
Summary for 2OXU
| Entry DOI | 10.2210/pdb2oxu/pdb |
| Related | 1RMZ 1Y93 2oxw 2oxz 2oy2 2oy4 |
| Descriptor | Macrophage metalloelastase, ZINC ION, CALCIUM ION, ... (4 entities in total) |
| Functional Keywords | mmp-12, matrix metalloproteinase, hydrolase |
| Biological source | Homo sapiens (human) |
| Cellular location | Secreted, extracellular space, extracellular matrix : P39900 |
| Total number of polymer chains | 1 |
| Total formula weight | 17866.72 |
| Authors | Calderone, V.,Bertini, I.,Fragai, M.,Luchinat, C.,Maletta, M.,Yeo, K.J. (deposition date: 2007-02-21, release date: 2007-03-06, Last modification date: 2023-08-30) |
| Primary citation | Bertini, I.,Calderone, V.,Fragai, M.,Luchinat, C.,Maletta, M.,Yeo, K.J. Snapshots of the reaction mechanism of matrix metalloproteinases. ANGEW.CHEM.INT.ED.ENGL., 45:7952-7955, 2006 Cited by PubMed: 17096442DOI: 10.1002/anie.200603100 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.24 Å) |
Structure validation
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