2OUZ

Crystal Structure of Estrogen Receptor alpha-lasofoxifene complex

Summary for 2OUZ

• Entry DOI: 10.2210/pdb2ouz/pdb
• Related: 1ERE 1ERR
• Descriptor: Estrogen receptor, (5R,6S)-6-PHENYL-5-[4-(2-PYRROLIDIN-1-YLETHOXY)PHENYL]-5,6,7,8-TETRAHYDRONAPHTHALEN-2-OL (3 entities in total)
• Functional Keywords: nuclear receptor, serm, estrogen, hormone-growth factor complex, hormone/growth factor
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 29302.57

Authors

Vajdos, F.F.,Pandit, J. (deposition date: 2007-02-12, release date: 2007-05-08, Last modification date: 2023-08-30)

• Primary citation: Vajdos, F.F.,Hoth, L.R.,Geoghegan, K.F.,Simons, S.P.,LeMotte, P.K.,Danley, D.E.,Ammirati, M.J.,Pandit, J.; The 2.0 A crystal structure of the ER{alpha} ligand-binding domain complexed with lasofoxifene; Protein Sci., 16:897-905, 2007; PubMed: 17456742; DOI: 10.1110/ps.062729207

Experimental method

X-RAY DIFFRACTION (2 Å)