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2OUZ

Crystal Structure of Estrogen Receptor alpha-lasofoxifene complex

Functional Information from PDB Data
site_idAC1
Number of Residues9
DetailsBINDING SITE FOR RESIDUE C3D A 999
ChainResidue
ALEU346
AALA350
AASP351
AGLU353
ATRP383
ALEU391
AARG394
AMET421
ALEU525

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues3
DetailsBINDING: BINDING => ECO:0000269|PubMed:9338790, ECO:0000269|PubMed:9600906, ECO:0007744|PDB:1A52, ECO:0007744|PDB:1ERE
ChainResidueDetails
AGLU353
AARG394
AHIS524

site_idSWS_FT_FI2
Number of Residues1
DetailsMOD_RES: Phosphotyrosine; by Tyr-kinases => ECO:0000269|PubMed:7539106
ChainResidueDetails
ATYR537

site_idSWS_FT_FI3
Number of Residues1
DetailsLIPID: S-palmitoyl cysteine => ECO:0000250
ChainResidueDetails
ACYS447

226707

PDB entries from 2024-10-30

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