2OSL
Crystal structure of Rituximab Fab in complex with an epitope peptide
Summary for 2OSL
Entry DOI | 10.2210/pdb2osl/pdb |
Descriptor | light chain of the Rituximab Fab fragment,light chain of the Rituximab Fab fragment, heavy chain of the Rituximab Fab fragment,heavy chain of the Rituximab Fab fragment, B-lymphocyte antigen CD20, ... (4 entities in total) |
Functional Keywords | fab-peptide complex, rituximab, chimeric antibody, immune system |
Biological source | Mus musculus (house mouse) More |
Total number of polymer chains | 6 |
Total formula weight | 99328.43 |
Authors | |
Primary citation | Du, J.,Wang, H.,Zhong, C.,Peng, B.,Zhang, M.,Li, B.,Huo, S.,Guo, Y.,Ding, J. Structural basis for recognition of CD20 by therapeutic antibody Rituximab J.Biol.Chem., 282:15073-15080, 2007 Cited by PubMed: 17395584DOI: 10.1074/jbc.M701654200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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