2NPP

Structure of the Protein Phosphatase 2A Holoenzyme

Summary for 2NPP

• Entry DOI: 10.2210/pdb2npp/pdb
• Related: 2IE3 2IE4
• Related PRD ID: PRD_000212
• Descriptor: Protein Phosphatase 2, regulatory subunit A (PR 65), alpha isoform, Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform, Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform, ... (5 entities in total)
• Functional Keywords: heat repeat, signaling protein, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• Biological source: Homo sapiens (human); More
• Cellular location: Cytoplasm: P67775; Nucleus: Q13362
• Total number of polymer chains: 8
• Total formula weight: 309667.67

Authors

Xu, Y.,Chen, Y.,Xing, Y.,Chao, Y.,Shi, Y. (deposition date: 2006-10-28, release date: 2006-12-12, Last modification date: 2023-11-15)

• Primary citation: Xu, Y.,Xing, Y.,Chen, Y.,Chao, Y.,Lin, Z.,Fan, E.,Yu, J.W.,Strack, S.,Jeffrey, P.D.,Shi, Y.; Structure of the protein phosphatase 2A holoenzyme; Cell(Cambridge,Mass.), 127:1239-1251, 2006; PubMed: 17174897; DOI: 10.1016/j.cell.2006.11.033

Experimental method

X-RAY DIFFRACTION (3.3 Å)