2ME8
Solution Structure of BCL-xL in its p53-bound conformation determined with selective isotope labelling of I,L,V sidechains
Summary for 2ME8
Entry DOI | 10.2210/pdb2me8/pdb |
Related | 2ME9 2MEJ |
NMR Information | BMRB: 19520 |
Descriptor | Bcl-2-like protein 1 (1 entity in total) |
Functional Keywords | bcl-xl, p53, apoptosis, bcl-2 family, cytoplasmic p53, selective labeling |
Biological source | Homo sapiens (human) |
Cellular location | Isoform Bcl-X(L): Mitochondrion inner membrane (By similarity): Q07817 |
Total number of polymer chains | 1 |
Total formula weight | 23669.94 |
Authors | Viacava Follis, A.,Grace, C.R.,Kriwacki, R.W. (deposition date: 2013-09-25, release date: 2014-04-30, Last modification date: 2024-05-15) |
Primary citation | Follis, A.V.,Llambi, F.,Ou, L.,Baran, K.,Green, D.R.,Kriwacki, R.W. The DNA-binding domain mediates both nuclear and cytosolic functions of p53. Nat.Struct.Mol.Biol., 21:535-543, 2014 Cited by PubMed: 24814347DOI: 10.1038/nsmb.2829 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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