2MC0
Structural Basis of a Thiopeptide Antibiotic Multidrug Resistance System from Streptomyces lividans:Nosiheptide in Complex with TipAS
Summary for 2MC0
Entry DOI | 10.2210/pdb2mc0/pdb |
Related | 1NY9 2mbz |
NMR Information | BMRB: 19422 |
Related PRD ID | PRD_001172 |
Descriptor | HTH-type transcriptional activator TipA, nosiheptide, 4-(hydroxymethyl)-3-methyl-1H-indole-2-carboxylic acid (3 entities in total) |
Functional Keywords | bacterial protein, streptomyces lividans, transcriptional activation, tipas-nosiheptide complex, transcriptional activator-antibiotic complex, protein/thiopeptide, multidrug recognition, transcription activator-antibiotic complex, transcription activator/antibiotic |
Biological source | Streptomyces lividans More |
Total number of polymer chains | 2 |
Total formula weight | 17986.64 |
Authors | Habazettl, J.,Allan, M.G.,Jensen, P.,Sass, H.,Grzesiek, S. (deposition date: 2013-08-12, release date: 2014-12-10, Last modification date: 2023-11-15) |
Primary citation | Habazettl, J.,Allan, M.,Jensen, P.R.,Sass, H.J.,Thompson, C.J.,Grzesiek, S. Structural basis and dynamics of multidrug recognition in a minimal bacterial multidrug resistance system Proc.Natl.Acad.Sci.USA, 111:E5498-E5507, 2014 Cited by PubMed: 25489067DOI: 10.1073/pnas.1412070111 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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