2MBZ

Structural Basis of a Thiopeptide Antibiotic Multidrug Resistance System from Streptomyces lividans:Promothiocin A in Complex with TipAS

Summary for 2MBZ

• Entry DOI: 10.2210/pdb2mbz/pdb
• Related: 1NY9
• NMR Information: BMRB: 19421
• Related PRD ID: PRD_001255
• Descriptor: HTH-type transcriptional activator TipA, Promothiocin A (2 entities in total)
• Functional Keywords: tipas/promothiocin a, protein/antibiotic, protein/thiopeptide, multidrug recognition, transcriptional activator, transcription activator-antibiotic complex, transcription activator/antibiotic
• Biological source: Streptomyces lividans; More
• Total number of polymer chains: 2
• Total formula weight: 17526.11

Authors

Habazettl, J.,Allan, M.G.,Jensen, P.,Sass, H.,Grzesiek, S. (deposition date: 2013-08-12, release date: 2014-12-10, Last modification date: 2023-11-15)

• Primary citation: Habazettl, J.,Allan, M.,Jensen, P.R.,Sass, H.J.,Thompson, C.J.,Grzesiek, S.; Structural basis and dynamics of multidrug recognition in a minimal bacterial multidrug resistance system.; Proc. Natl. Acad. Sci. U.S.A., 111:E5498-E5507, 2014; PubMed: 25489067; DOI: 10.1073/pnas.1412070111

Experimental method

SOLUTION NMR